Is your skin constantly itchy, no matter how much you scratch or apply lotion? Many people assume it is simply due to dryness, allergies, or a change in weather. However, if you have tried multiple remedies and the itch still will not go away, it is important to pay closer attention. Persistent itching may not just be a skin issue; sometimes it can signal an underlying health problem, particularly related to your kidneys. Common Causes of Itchy Skin